Germanium Sesquioxide
Organic Germanium

Bis (2-Carboxyethylgermanium)sesquioxide

The Manufacturing Process Does Matter

Contamination of germanium sesquioxide with dangerous levels of inorganic salts occurs as a result of extreme carelessness or a wanton act. Meticulous process design and careful process controls virtually eliminate the likelihood of such contamination. However, germanium dioxide (GeO2) is not the only potential hazard associated with germanium sesquioxide.

Nitrogen content is indicative of an inferior manufacturing process, utilizing acrylonitrile. Acrylonitrile, also called vinyl cyanide, is a mutagenic carcinogen and any manufacturer utilizing this process is left with a serious dilemma. If excess acrylonitrile is not used, there is the risk of germanium dioxide (GeO2) contamination. When excess acrylonitrile is used, it invariably ends up in the final product for consumption.

The toxic effects of acrylonitrile are not the only concern. During the hydrolysis step of the manufacturing process, some of the excess acrylonitrile is converted to acrylamide. Acrylamide is a known toxin suspected of causing cancer, birth defects, heritable genetic mutations, neurological damage, and effects that can take years to become apparent.

Without testing, it is usually impossible to know what reagents were used in the manufacturing process for germanium sesquioxide. However, a simple google search can still be quite revealing. Designed Nutritional Products strongly recommends avoiding any source of germanium sesquioxide touting acrylonitrile as a reagent in its published manufacturing process. Designed Nutritional’s germanium sesquioxide is produced with our own process which completely avoids any nitrogen containing reagents that lead to undesirable contaminants.

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